Kambo Peptides

Phyllomedusin – produces contraction at the muscle level and increases secretion of the entire gastrointestinal tract such as the salivary glands, stomach, small and large intestine, pancreas, and gallbladder. These are the main parts responsible for the deep purge produced by the administration of Kambo.

Phyllokinin & Phyllomedusins – are potent vasodilators, increasing the permeability of the blood-brain barrier both for their own access as well as for that of other active peptides. Within this family are the medusins, which also have antimicrobial and antifungal properties.

Caeruleins & Sauvagines – are peptides with myotropic properties on the muscles, producing a contraction of the colon and urinary bladder. They produce a drop in blood pressure accompanied by tachycardia. They stimulate the adrenal cortex and pituitary gland, contributing to greater sensory perception and increased resistance. Both peptides possess a great analgesic power, contributing to the increase of physical strength, the capacity to confront physical pain, stress, disease, and diminish the symptoms of fatigue.

Dermorphin & Deltorphin – are small peptides that are selective agonists of the opiate delta receptors; 4,000x more potent than morphine and 40x more potent than the endogenous endorphins.

Adenoregulins – works on the human body through the adenosine receptors, which is a fundamental component throughout all human cellular fuel. These receptors may offer a target for the treatment of depression, stroke and cognitive loss diseases, such as Alzheimer’s disease and Parkinson’s. 

Antimicrobial Peptides – Dermaseptins, Adenoregulins, Plasticins, and Philloseptins form part of a family of a broad spectrum of antimicrobial peptides involved in the defense of the frogs’ bare skin against microbial invasion. Peptides Dermaseptin B2 and B3 are effective in killing certain types of cancer cells.

Bradykinins – produce vasodilation, contraction of the non-vascular smooth muscle, increase vascular permeability, and are related to the mechanism of inflammatory pain.

Bombesins – increase pancreatic secretion, intestinal myoelectric activity, and smooth muscle contractibility.

Ceruleins – stimulate gastric, bile, and pancreatic secretions, as well as certain smooth muscles.

Tryptophilins – are neuropeptides that are broadening perspectives on how the human brain works.